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Several sclerosis is an autoimmune, frantic and desmyelinization. Multiple sclerosis: Compound sclerosis is an autoimmune, revolutionary and desmyelinization disease central tense system CNS of unknown etiology and critical evolution. There divergent etiological hypotheses talking of a close interrelation among predisposing inherited factors and dissimilar environmental factors, able to give raise on the way to autoimmune response at central fretful system level.

Hypothesis of autoimmune pathogeny is based on studio of experimental models, and findings in biopsies of affected patients by disease. Accumulative data come in that the oxidative stress plays a main role in pathogenesis of multiple sclerosis. Oxygen kneejerk species generated by macrophages has been involved as mediators of demyelinization and of axon wound, in experimental autoimmune encephalomyelitis as well as strictly in multiple sclerosis.

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